England fast bowler Brydon Carse has been ruled out of the third and final one-day international against South Africa at Headingley on Sunday with a bruised right toe.
Carse, 26, suffered the injury in the first game at Durham on Tuesday, where he took 1-46 from nine overs.
The right-armer left the England squad on Saturday morning and will be further assessed over the next week.
The series is level at 1-1 after England's 118-run win on Friday.