Colombia has announced that the country's most wanted drug trafficker will be extradited to the US after he was captured in a raid.
Dairo Antonio Úsuga, known as Otoniel, was seized after a joint army, air force and police operation on Saturday.
He led the country's largest criminal gang and has been on the US Drug Enforcement Agency's most wanted list for years.
US officials had placed a $5m (£3.6m) bounty on his head.
They accused him of importing at least 73 metric tonnes of cocaine into the country between 2003 and 2014.
What will happen to him?
Colombia's Defence Minister Diego Molano told El Tiempo newspaper that the next step for officials was to comply with the US extradition order.
Authorities have now taken Otoniel to a military base in the capital Bogotá ahead of his extradition, according to newspaper El Nuevo Siglo.
Being locked up in a jail thousands of miles from their home country, in a place where they have few connections and no means to intimidate guards or prison directors is a fate many Colombian drug traffickers fear.
The late drug lord Pablo Escobar said that he would prefer "lying in a grave in Colombia than being locked up in a cell in the US".
Except for a six-year period between 1991 and 1997, when Colombia's constitution banned extraditions of Colombian citizens, a number of top level traffickers facing indictments in the US have been sent to stand trial there.
Among them are the co-founder of the Medellín cartel, Carlos Lehder, drug lord Daniel "The Madman" Barrera and paramilitary leader Salvatore Mancuso.
Otoniel, who was indicted in the the US in 2009, will faces a number of charges, including sending shipments of cocaine to the US, killing police officers and recruiting children.
How was he caught?
Otoniel was captured in his rural hideout in Antioquia province in north-western Colombia, close to the border with Panama.
The operation involved 500 soldiers supported by 22 helicopters. One police officer was killed.
Otoniel had used a network of rural safe houses to move around and evade the authorities, and did not use a phone, instead relying on couriers for communication.
In the past, police have found special orthopaedic mattresses for Otoniel in these sparse homes, as he suffered back pain from a herniated disc.
Police chief Jorge Vargas has said the drug lord was fearful of capture, "never approaching inhabited areas".
BACKGROUND: Colombia's hunt for an elusive drug lord
But El Tiempo reported that authorities managed to pinpoint the location where he was eventually captured two weeks ago.
Chief Vargas said his movements were traced by more than 50 signal intelligence experts using satellite imagery. US and UK agencies were involved in the search.
Mr Duque described the operation as "the biggest penetration of the jungle ever seen in the military history of our country".
Colombia's armed forces later released a photo showing its soldiers guarding Otoniel, who was in handcuffs and wearing rubber boots.
There have been several huge operations involving thousands of officers to capture the 50-year-old in recent years.
Analysis box by Katy Watson, South America correspondent
There's no doubt this is seen as a coup by Colombian authorities - they've been trying to capture Otoniel for several years now. The Gulf Cartel is a formidable and violent organisation with a great deal of power.
And the comparisons with Pablo Escobar are understandable. Otoniel is a household name and has been hugely powerful, especially in the north west of the country.
"In South America, there is no larger cocaine trafficker," says Toby Muse, author of Kilo: Inside the Cocaine Cartels. "We are living in the golden age of cocaine, we are producing more cocaine than ever - that's a fact."
But the parallels perhaps stop there - Otoniel is not as well-known outside of Colombia. And speak to people who lived in the country at the peak of Pablo Escobar's power, many feel they were more frightening times.
The question is, will Otoniel's capture impact the trade of the illicit drug? It's hard to know now. We'll have to see what happens in the coming months but most experts seem to think that while demand for cocaine remains strong, it's likely there will be new "capos" rising to the top to replace him.
Who is Otoniel?
Born in Antioquia in the early 1970s, Otoniel jumped between several guerrilla and paramilitary groups - including the Farc (Revolutionary Armed Forces of Colombia), the major Marxist-Leninist rebel group, and the United Self-Defence Forces of Colombia (AUC), a far-right paramilitary and drug trafficking gang.
When the AUC dissolved in 2005, he began working for the drug lord Daniel Rendón Herrera, known as Don Mario - head of the Urabeños, which later became known as the Gulf Clan.
Otoniel then took charge of the group after its previous leader - his brother - was killed by police in a raid on a New Year's Eve party almost 10 years ago.
Colombia's security forces labelled the gang as the country's most powerful criminal organisation, while authorities in the US describe it as "heavily armed [and] extremely violent".
The gang, which operates in many provinces and has extensive international connections, is engaged in drug and people smuggling, illegal gold mining and extortion.
It is believed to have about 1,800 armed members, who are mainly recruited from far-right paramilitary groups. Members have been arrested in Argentina, Brazil, Honduras, Peru and Spain.
The gang controls many of the routes used to smuggle drugs from Colombia to the US, and as far away as Russia.
The Colombian government, however, believes it has decimated its numbers in recent years, forcing many leading members to hide in remote regions in the jungle.