Amadou Haidara scored the game's only goal, finding the net with a fierce drive from outside the area.

Mohamed Magassouba's side will face Group D runners-up Ivory Coast in the last 16 on Monday.

Angola, who finish third in Group E, miss out on a place in the knockout stages.

Mali made eight changes to the side that drew 1-1 with Tunisia on Friday and they rode their luck early on, Gelson shooting straight at goalkeeper Djigui Diarra before Mateus dragged another effort wide of the near post.

A draw would have been enough for Angola to advance, but they fell behind when Haidara fired an unstoppable shot past Tony Cabaca eight minutes before half-time.

Second-half substitute Moussa Marega missed the chance to double Mali's lead late on, blazing over the crossbar from an acute angle.

Tunisia join Mali in the last 16 after drawing 0-0 with Mauritania in Suez.

Analysis

By BBC World Service Sport's Ben Sutherland

Angola's Afcon campaign spluttered and died whereas Mali surprisingly top Group E with 3 wins from 3.

This was a game that had absolutely nothing to recommend it apart from the beautiful, crisply taken Haidara goal.

Having watched Benin grind out the 0-0 draw they needed before the game in the same stadium, Angola were set up with exactly the same plan - to get the draw.

But when Haidara netted eight minutes before the break their plan was in pieces - and they had nowhere else to go.

The result will be celebrated most in South Africa - Angola's defeat means that Bafana Bafana go through as one of the four best third-place finishers.

Mali's caretaker coach Magassouba is making a strong case to stay on permanently.