Daniel Casey will be the series' writer and executive producer. He has action credits on the screenplay for F9: The Fast Saga and made contributions to sci-fi films Kin and 10 Cloverfield Lane. Variety noted some of the other executive producers, but there have been no details shared yet about the cast or plot of the project. Since a large part of the original Mass Effect games' appeal was players making their own choices about Commander Shepard's moral compass and love life, it seems likely that a show would want to tell an original story within that universe rather than retreading the same path as the trilogy.

Amazon had a huge win with its TV adaptation of Fallout earlier this year, and it seems the company is going to continue mining video games for source material. After some stumbles, Amazon is also reviving its plans for a live-action God of War show.