Everton have confirmed that Turkey international striker Cenk Tosun has suffered an anterior cruciate ligament injury and will have surgery next week.
The 28-year-old joined Crystal Palace on loan for the rest of the season in January and made five appearances for the Eagles, scoring once.
Palace have an option for a permanent deal but Tosun suffered the serious injury during training on Monday.
He will spend his rehabilitation at Everton's Finch Farm training ground.
Turkey are scheduled to play on the opening day of Euro 2020 with a match against Italy in Rome on 12 June.
Tosun moved to Everton from Besiktas for £27m in January 2018.