Adwoa Safo was sacked by President Akufo-Addo on July 28, 2022, following her long absence at the Ministry.

In a letter responding to her Ministerial revocation letter dated August 5, 2022, Ms Safo expressed her gratitude to the President for the opportunity he gave her to serve in his government as a minister. The letter which she addressed to the President, was copied to the Vice President and the Chief of Staff.

She said, "It is with profound gratitude that I express utmost appreciation to you for the opportunity to serve as Minister in both terms of your government."