Ten-man Celtic suffered a damaging blow to their Scottish Premiership title hopes as Kai Andrews' late winner secured Hibernian a first victory at Parkhead since 2010 on a potentially pivotal day in an incredible season.

Three days after Martin O'Neill's side endured a bruising 4-1 Europa League defeat to Stuttgart at the same venue, Celtic Park was stunned again as the 73-year-old suffered his first domestic loss of the campaign.

Felix Passlack headed in his first Hibs goal from a bending Nicky Cadden cross on 24 minutes, marking the fourth time in five games Celtic have conceded first.

However, O'Neill's men responded once more following a spell of late first-half pressure when Benjamin Nygren nodded in from close range.

As the scarcely-believable news from West Lothian filtered through, with bottom side Livingston leading Rangers by two, Celtic fans attempted to whip up their team amid a Glasgow downpour.

However, a red card for Auston Trusty - awarded after an on-field VAR review - derailed the home side's momentum.

The Celtic defender was adjudged to have used excessive force with his arm when lashing out violently at Jamie McGrath before a corner for the hosts.

While Rangers staged a two-goal comeback, Hibs capitalised on their man advantage when Ante Suto set up Andrews to bury a sensational winner, earning a seismic victory that boosts their city rivals' title bid.

The result means Celtic stay third with a game in hand, six points adrift of leaders Hearts and two off Rangers, who host O'Neill's side in an Old Firm derby next Sunday.

This totally ludicrous Premiership season has a new chapter, and it could be decisive.

Celtic have been riding their luck of late. They have now gone behind in four of their past five matches, three of those in the domestic scene.

O'Neill's men had found late goals against Dundee, Livingston and Kilmarnock, but their fortune ran dry in the driving rain in this one.

Despite registering 21 shots, just three were on target - one of which was Nygren's 18th goal of the season.

The Swede also struck wide earlier in the first half before Alex Oxlade-Chamberlain - making his first Celtic start - blasted over.

Hibs were wasteful in the first period, Martin Boyle in particular with poor decision-making, but they showed bottle to grab this game when it was presented to them.

It would be unfair to purely frame this result as providing a helping hand to their Edinburgh rivals as this long-awaited victory in the east end of Glasgow underlines the Leith side's European credentials, with Motherwell five points ahead in fourth.

Celtic interim manager Martin O'Neill: "It's a setback, that's all it is. We're still in the race. There's not much room for error but we can still fight back.

"I thought we were absolutely terrific. The players put heart and soul into the game. No complaints on that side whatsoever."

Hibs head coach David Gray: "It's been a long time coming. That's twice we've been here [this season] and not lost.

"It shows we are capable if we go toe-to-toe, but it takes a level of performance that requires every man to be at their very best."

Celtic travel to Stuttgart on Thursday (17:45 GMT) for the second leg of their Europa League knockout play-off, with the tie all but over, before an Old Firm derby against Rangers at Ibrox next Sunday (12:00).

Hibs' next assignment is a Premiership trip to Dundee on Saturday (15:00).