English amateur Tyler Weaver will make his US Open debut after earning a qualifying spot on Monday.
US PGA Tour players Rickie Fowler and Max Homa were among the big names to miss out on what is known as 'golf's longest day'.
US Open hopefuls played 36 holes at 10 venues across the US and Canada in a bid to secure their spot, with a total of 47 available.
England Golf men's squad member Weaver, 22, was tied for third at 11 under to become one of three amateurs to qualify in Atlanta, with 17-year-old American Mason Howell leading the way.
England's Matt Wallace ended the day at seven under par to be one of seven qualifiers in Ontario, along with Denmark's Thorbjorn Olesen.
South Africa's Erik van Rooyen finished first in Columbus, Ohio, with Fowler and Homa missing out in a five-man play-off as fellow American Cameron Young claimed the final spot.
Homa, 34, was the only player carrying his bag at the event having recently split from his caddie and, with it going to a play-off, the world number 90 had to carry it for 38 holes.
At Woodmont in Maryland, Ryan McCormick and Trevor Cone took the first two spots, before Australia's Marc Leishman and American amateur Bryan Lee prevailed in a play-off for the other two.
The Florida event was suspended because of bad weather so play will resume on Tuesday.
Among those in contention is English amateur Luke Poulter, son of former world number five Ian Poulter.
Four spots are on offer at West Palm Beach and the 21-year-old was in fourth when play was halted, finishing the first round on 69.
Northern Ireland's Graeme McDowell, the 2010 US Open winner, is also in contention after a first round of 70, but his fellow countryman Tom McKibbin missed out.
This year's US Open takes place at Oakmont in Pennsylvania from 12-15 June.
Matt Vogt used to be a caddie there but is now a practising dentist in Indianapolis and managed to claim one of the two spots at the qualifier in Washington state.