The 28-year-old was forced to sit out his side's 1-0 defeat at Celta on Sunday having been forced off through injury in the 88th minute of the 3-1 Copa del Rey victory at Valencia last Thursday.

Williams' run of games began when he came off the bench in the second half of a 1-0 defeat to Atletico Madrid in 2016 in which former Liverpool and Chelsea striker Fernando Torres scored the only goal.

The northern Spanish club confirmed in a tweet: "(Williams) had not missed a match since April 20, 2016. Yesterday (Sunday) he was unable to play against Celta due to muscle overload."

Williams made one appearance for the Spanish senior team in a friendly against Bosnia in 2016 with his last appearances coming at the Euro Under-21 Championships in 2017.

The Bilbao-born player sealed a 3-1 victory against rivals Portugal in the group stage but Spain were eventually defeated by Germany in the final with Williams coming on as a second half substitute.

Having failed to win a further call up to the Spanish senior squad, Williams switched allegiances to the country of his parents, Ghana, ahead of the Qatar World Cup making his debut in a 3-0 friendly defeat by Brazil in September 2022.

Williams started all three matches in Qatar but failed to score as Ghana were eliminated at the group stage following 2-0 defeat by Uruguay.