Everton forward Richarlison scored twice on his first start for Brazil as they beat El Salvador 5-0 at FedExField in Maryland.
The 21-year-old won a penalty in the second minute, which was scored by Neymar for his 59th Brazil goal.
Richarlison doubled the lead with a curling strike, before Philippe Coutinho added a third.
Richarlison swept home his second in the 50th minute, with Marquinhos heading home a fifth late on.
Victory was Brazil's second in succession as they rebuild after exiting the World Cup at the quarter-final stage with defeat by Belgium.
Richarlison, who made his debut as a second-half substitute in Saturday's 2-0 win over the USA, has scored three Premier League goals this season after moving to Everton in the summer in a £50m deal.
Elsewhere, Argentina - who were without Barcelona forward Lionel Messi - drew 0-0 with Colombia in New Jersey.
Both sides had stand-in coaches for the game, with Argentina yet to replace Jorge Sampaoli, and Jose Pekerman having resigned as Colombia boss.
A second-half goal from 19-year old New York Red Bulls midfielder Tyler Adam gave the USA a 1-0 win against 10-man Mexico in Nashville.
Four minutes before Adam's winner - his first international goal - Angel Zaldivar was shown a red card for a two-footed challenge on US captain Wil Trapp.