Ghana’s main opposition party has given a three-week ultimatum to the central bank governor and his deputy to resign.
The National Democratic Congress accuses Ernest Addison of recklessness and mismanaging the bank - with the bank accused of illegally printing money and spending over $8.6m (£6.7m) on travel expenses.
A recent annual report of the central bank indicated it recorded about $5.4bn in losses last year.
The bank has denied the NDC allegations and attributed the losses to a domestic debt restructuring deal that was part of the conditions for securing a bailout from the International Monetary Fund.
Ghana is currently trying to navigate its way out of its worst economic crisis in a generation.
The country’s inflation hit a record 54% in December last year.
This May the country secured a $3bn IMF bailout programme to address the economic crisis.