The awards ceremony, broadcast live on FOX and hosted by rapper Ludacris, saw Burna Boy taking the spot ahead of his compatriots.
Adding to the Nigerian triumph, Rema’s ‘Calm Down’ featuring Selena Gomez also took the title of Best Collaboration of the Year.
Meanwhile, American pop icons Beyoncé and Cher were honoured with the iHeart Innovator Award and the iHeart Icon Award, respectively.
Taylor Swift dominated the night with an impressive six awards, including Artist of the Year and Pop Artist of the Year.
Burna Boy and Rema now join the ranks of Wizkid and Tems as the only Nigerian artists to have received an iHeart Radio Music Award.
This victory comes as a relief for Burna Boy, who had faced disappointments at previous award shows, including the 2023 BET Hip-hop Awards and the 2024 Grammys.