Clothing giant Primark has gone from making £650m in sales a month to nothing as the coronavirus has forced it to close in Europe and the US.
Primark owner Associated British Foods "has been squarely in the path of this pandemic," said boss George Weston.
Without furlough support from European states, many of Primark's 68,000 staff would have been made redundant, he said.
The company has also written down the value of its clothing stock by £284m.
"From making sales of £650m each month, since the last of our stores closed on 22 March, we have sold nothing," Mr Weston said.
He added that while he would "love" to be able to reopen Primark stores, "I know that we must not do so until we have suppressed this disease".
Mr Weston also also said that when stores can reopen, "we must make our Primark stores safe for our staff and our customers, even if that means ensuring there are fewer people shopping at any one time and so accepting lower sales at least until the remaining risk is minimal".
"In time we can rebuild the profits. We can't replace the people we lose."
Mr Weston paid tribute to two workers at AB Foods who within the last three weeks have died from coronavirus.
Mario Marioli worked for 40 years at a yeast plant the firm owns in Italy, and Claudio Maini worked at Italian balsamic vinegar maker Acetum for 20 years.
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AB Foods said it had paid Primark's suppliers for stock it has received and will set up a fund to ensure workers who make those clothes are paid.
This move comes at a time when competing retailers have asked suppliers for payment holidays and cuts.
Earlier this month, New Look said it would suspend payments to suppliers for existing stock "indefinitely", telling them in a letter that the stock can be collected by its owners.
AB Foods is cash-rich by comparison with many companies with a High Street presence.
It has £801m in cash and a £1.09bn loan agreed, which it has recently drawn down in case banks have trouble lending in the future.
As well as Primark, Associated British Foods owns food brands including Twinings tea, Blue Dragon sauces and Ovaltine.
For these and other businesses outside Primark, the company has kept its financial forecasts for the year the same.
However, while many clothing rivals have been able to makes sales online, Primark sells only gift cards through its website.
This is a big problem for AB Foods as Primark usually contributes about two-thirds of the company's profits.
"Although AB Foods derives some benefit from product and geographical diversification in other parts of the group, the impact of the loss of Primark income, even if temporary, is a major blow," said Richard Hunter, head of markets at Interactive Investor.
The shares fell 4.2% in London trading to 1,903.5 pence apiece, valuing the firm at about £15bn. The shares changed hands at 2,708 pence each in February.
Overall, it said net profit for the first half of the year fell to £217m from £389m.
"Our food businesses have continued production at all facilities, maintaining their essential output to support the food, animal feed and pharmaceutical supply chains. This has been and remains a key priority for us," said Mr Weston.
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